After you complete your edits and the review of the document, you can sign off the article by clicking on the Approve button at the top right corner of the interface.
Choose the required option in the Sign-off Manuscript page and click Continue.
The document has now been signed off and no further changes can be made.
Note 1: You have to respond to all queries that are addressed to you before signing off an article to the next stage.
Note 2: For documents with numbered reference format, the system would renumber the references in sequential order before the document is signed off.